루테인
루테인 · 눈건강 · C40H56O2

Lutein is a carotenoid pigment found in high concentrations in the macula of the human eye, where it plays a crucial role in protecting against oxidative stress and blue light damage. It is also present in various fruits and vegetables, particularly dark green leafy ones.

Aliases
Lutein루테인
Active Compounds
Lutein
Functions (4)
Blue Light Filtrationstrongnervous

Lutein absorbs high-energy blue light, reducing phototoxic damage to the retina.

Antioxidant Activitystrongnervous

Lutein neutralizes reactive oxygen species, protecting retinal cells from oxidative stress.

Age-Related Macular Degeneration (AMD) Preventionmoderatenervous

By filtering blue light and reducing oxidative stress, lutein helps prevent or slow the progression of AMD.

Cataract Preventionmoderatenervous

Lutein's antioxidant properties may reduce lens oxidation, potentially lowering cataract risk.

Compound Benefits (2)
CompoundBenefitEvidenceConfidence
LuteinImproved Visual Acuitymoderate
75%
LuteinReduced Glare Sensitivitymoderate
70%
Recommended Dosage
620 mg· Clinical studies often use doses between 6-20 mg per day; higher doses up to 40 mg have been used without significant adverse effects.
Interactions (2)
AntagonistBeta-CaroteneHigh doses of beta-carotene may compete with lutein for absorption.moderate
CautionWarfarinLutein may have a mild anticoagulant effect; monitor blood clotting parameters.mild
Regulatory Status
FDA (US)
GRAS
MFDS (Korea)
건강기능식품 고시형
EFSA (EU)
approved health claim
Natural Sources
SpinachKaleEgg yolkCornOrange pepperKiwi fruitGrapesZucchiniSquash
Frequently Paired Ingredients (8)
Processed Productsmoderate
4 co-occurrencesmarket

Processed products often serve as carriers or stabilizers for lutein, enhancing its bioavailability.

Improved absorption
Fruit and Vegetable Processed Productsmoderate
4 co-occurrencesmarket

These products provide additional antioxidants that complement lutein's effects.

Enhanced antioxidant protection
Enzyme-treated Steviapreliminary
3 co-occurrencesmarket

Used as a natural sweetener to improve taste without affecting lutein's efficacy.

Better taste
Magnesium Stearatestrong
3 co-occurrencesmarket

Acts as a lubricant in supplement manufacturing, ensuring consistent dosage.

Consistent dosage
Mixed Food Additivesmoderate
3 co-occurrencesmarket

Enhances stability and shelf-life of lutein supplements.

Increased stability
Zinc Oxidemoderate
3 co-occurrencesmarket

Provides additional eye health benefits, complementing lutein's role.

Improved eye health
Glucosepreliminary
3 co-occurrencesmarket

Used as a filler or to enhance energy levels, supporting overall supplement efficacy.

Energy boost
Vitamin Cstrong
3 co-occurrencesmarket

Works synergistically with lutein to enhance antioxidant effects.

Enhanced antioxidant effects
Sources (3)
1
Biologic mechanisms of the protective role of lutein and zeaxanthin in the eyejournal· Annual Review of Nutrition

Discusses the protective mechanisms of lutein and zeaxanthin in eye health.

2
Lutein: Overview, Uses, Side Effects, Precautions, Interactions, Dosing and Reviewsdatabase· WebMD

Provides a comprehensive overview of lutein, including uses and safety information.

3
The Effect of Lutein on Eye and Extra-Eye Healthjournal· Nutrients

Reviews the effects of lutein on eye health and other health aspects.