Milk thistle (Silybum marianum) is a plant native to the Mediterranean region, traditionally used for liver health. Its seeds contain silymarin, a complex of flavonolignans known for antioxidant and hepatoprotective properties.
Silymarin stabilizes hepatocyte membranes and acts as an antioxidant, reducing free radical production.
Silymarin scavenges free radicals and increases superoxide dismutase activity, reducing oxidative stress.
Silymarin inhibits NF-κB pathway, reducing pro-inflammatory cytokine production.
| Compound | Benefit | Evidence | Confidence |
|---|---|---|---|
| Silymarin | Liver detoxification support | moderate | 70% |
| Silibinin | Antioxidant protection | moderate | 70% |
Used as a solvent and carrier for active ingredients.
Enhances the potency of milk thistle by providing a concentrated form.
Supports liver function and enhances detoxification processes.
Works with milk thistle to support liver health and reduce oxidative stress.
Used as a filler and stabilizer to improve the formulation.
Acts as a lubricant to aid in the manufacturing process.
Supports energy production and works synergistically with other B vitamins.
Supports carbohydrate metabolism and energy production.
Comprehensive overview of milk thistle's uses, dosing, and safety.
Detailed information on milk thistle's hepatotoxicity and clinical use.
Consumer-friendly information on milk thistle's uses and interactions.