오메가3
오메가-3 지방산 · 혈관건강

Omega-3 fatty acids are essential polyunsaturated fats crucial for cardiovascular health, known for their anti-inflammatory and lipid-lowering properties.

Aliases
Omega-3 Fatty Acidsn-3 Fatty Acids오메가-3 지방산n-3 지방산
Active Compounds
Eicosapentaenoic Acid (EPA)Docosahexaenoic Acid (DHA)
Functions (4)
Triglyceride Reductionstrongcardiovascular

Omega-3 fatty acids lower triglyceride levels by suppressing lipogenic gene expression, increasing beta-oxidation of fatty acids, and enhancing lipoprotein lipase activity.

Anti-Inflammatory Effectsstrongcardiovascular

Omega-3 fatty acids reduce inflammation by serving as substrates for specialized pro-resolving mediators, such as resolvins and protectins, which actively resolve inflammation.

Anti-Arrhythmic Propertiesmoderatecardiovascular

Omega-3 fatty acids stabilize cardiac myocyte membranes, reducing susceptibility to fatal ventricular arrhythmias.

Blood Pressure Reductionmoderatecardiovascular

Omega-3 fatty acids induce vasodilation and improve endothelial function, leading to reduced blood pressure.

Compound Benefits (2)
CompoundBenefitEvidenceConfidence
Eicosapentaenoic Acid (EPA)Reduction of Triglyceride Levelsstrong
90%
Docosahexaenoic Acid (DHA)Improved Endothelial Functionmoderate
80%
Recommended Dosage
10004000 mg· The FDA recommends consuming no more than 5 grams per day of EPA and DHA combined from dietary supplements. Typical doses for cardiovascular benefits range from 1,000 to 4,000 mg per day.
Interactions (2)
CautionAnticoagulant Medications (e.g., Warfarin)High doses of omega-3 fatty acids may increase bleeding risk when taken with anticoagulant medications.moderate
CautionAntiplatelet Agents (e.g., Aspirin)Omega-3 fatty acids may enhance the effects of antiplatelet agents, increasing bleeding risk.moderate
Regulatory Status
FDA (US)
dietary supplement
MFDS (Korea)
건강기능식품 고시형
EFSA (EU)
approved health claim
Natural Sources
SalmonMackerelSardinesFlaxseedsChia SeedsWalnuts
Frequently Paired Ingredients (8)
EPA and DHA containing oilstrong
9 co-occurrencesmarket

EPA and DHA are types of Omega-3 fatty acids, which are often combined to enhance cardiovascular and anti-inflammatory benefits.

Improved heart healthReduced inflammation
d-alpha-Tocopherolstrong
7 co-occurrencesmarket

d-alpha-Tocopherol, a form of Vitamin E, is combined with Omega-3 to prevent oxidation of the fatty acids, enhancing stability and efficacy.

Enhanced antioxidant protectionImproved Omega-3 stability
Processed oilsmoderate
6 co-occurrencesmarket

Processed oils are used as carriers or fillers to improve the delivery and absorption of Omega-3 supplements.

Improved absorptionEnhanced delivery
Beeswaxmoderate
4 co-occurrencesmarket

Beeswax is used as a stabilizer and thickening agent in Omega-3 supplements, helping to maintain consistency and shelf life.

Improved product stabilityExtended shelf life
Purified waterpreliminary
4 co-occurrencesmarket

Purified water is used as a solvent or carrier in liquid Omega-3 formulations to ensure proper mixing and delivery.

Enhanced mixingImproved delivery
D-sorbitol solutionpreliminary
3 co-occurrencesmarket

D-sorbitol solution is used as a sweetener and humectant in Omega-3 supplements, improving taste and moisture retention.

Improved tasteEnhanced moisture retention
Vitamin Estrong
3 co-occurrencesmarket

Vitamin E is often added to Omega-3 supplements to prevent oxidation and enhance the antioxidant profile.

Enhanced antioxidant protectionPrevention of Omega-3 oxidation
Other edible oil productsmoderate
3 co-occurrencesmarket

Other edible oils are used to enhance the absorption and bioavailability of Omega-3 fatty acids.

Improved bioavailabilityEnhanced absorption
Sources (3)
1
Omega-3 Fatty Acids - StatPearls - NCBI Bookshelfdatabase· NCBI

Comprehensive overview of omega-3 fatty acids' mechanisms and health effects.

2
Omega-3 Supplements: What You Need To Know | NCCIHgovernment· NCCIH

Information on omega-3 supplements and their cardiovascular benefits.

3
Omega-3 Fatty Acids - Consumergovernment· NIH ODS

Consumer-focused factsheet on omega-3 fatty acids.