유산균(프로바이오틱스)
유산균 · 장건강

Probiotics are live microorganisms that, when administered in adequate amounts, confer health benefits to the host. They primarily consist of bacteria from genera such as Lactobacillus and Bifidobacterium, and are commonly found in fermented foods and dietary supplements.

Aliases
ProbioticsLactic Acid Bacteria프로바이오틱스유산균
Active Compounds
Lactobacillus speciesBifidobacterium speciesSaccharomyces boulardii
Functions (5)
Gut Microbiota Modulationstrongdigestive

Probiotics help balance the gut microbiota by inhibiting pathogenic bacteria and promoting beneficial bacteria.

Immune System Modulationmoderateimmune

Probiotics modulate the immune response by enhancing the activity of certain immune cells and promoting anti-inflammatory cytokine production.

Enhancement of Intestinal Barrier Functionmoderatedigestive

Probiotics strengthen the intestinal barrier by increasing mucin production and enhancing tight junction integrity.

Production of Antimicrobial Substancesmoderatedigestive

Probiotics produce substances like bacteriocins and organic acids that inhibit the growth of harmful bacteria.

Neuromodulation via Gut-Brain Axispreliminarynervous

Probiotics influence the gut-brain axis by producing neurotransmitters like serotonin and GABA, potentially affecting mood and behavior.

Compound Benefits (3)
CompoundBenefitEvidenceConfidence
Lactobacillus rhamnosus GGReduction of acute diarrhea durationstrong
90%
Bifidobacterium animalis subsp. lactis BB-12Improvement of bowel regularitymoderate
80%
Saccharomyces boulardiiPrevention of antibiotic-associated diarrheamoderate
80%
Recommended Dosage
100000000010000000000 CFU· Dosages typically range from 1 to 10 billion CFU per day, depending on the specific strain and health condition.
Interactions (2)
CautionAntibioticsAntibiotics may reduce the efficacy of bacterial probiotics; separate intake by at least two hours.moderate
ContraindicatedImmunosuppressantsUse of probiotics in immunocompromised individuals may increase risk of infections.severe
Regulatory Status
FDA (US)
dietary supplement
MFDS (Korea)
건강기능식품 고시형
EFSA (EU)
approved health claim
Natural Sources
YogurtKefirKimchiSauerkrautMisoTempeh
Sources (3)
1
Probiotics - Health Professional Fact Sheetgovernment· National Institutes of Health

Comprehensive overview of probiotics, including mechanisms and health benefits.

2
Mechanisms of Action of Probioticsjournal· Advances in Nutrition

Detailed review of probiotic mechanisms of action.

3
Probiotics: mechanism of action, health benefits and their application in food industriesjournal· Frontiers in Microbiology

Discusses probiotic mechanisms, health benefits, and applications in food.